POLD1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10315-50, MB10315-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P28340

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ICC/IF, FC

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: Possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction. Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis. Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 124 kDa; Observed MW: 124 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of POLD1 in K562 using POLD1 antibody, and DAPI., Western blot analysis of POLD1 in K562, C6, 3T3, Hela lysates using POLD1 antibody.

Alternative Name: CDC2; CRCS10; MDPL; POLD; POLD1

Immunogen: A synthetic peptide of human DNA Polymerase delta, catalytic subunit

Conjugate: Unconjugated

Modification: Unmodified