CdcA3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1935-50, ES1935-100

Citations, Manuals and MSDS Available upon request.

Background: domain:The KEN box is required for the association with the APC/C-Cdh1 complex., function:F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., PTM:Ubiquitinated and degraded by the APC/C-Cdh1 complex., subunit:Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex.,

Alternate Name: CDCA3; C8; GRCC8; TOME1; Cell division cycle-associated protein 3; Gene-rich cluster protein C8; Trigger of mitotic entry protein 1; TOME-1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human CDCA3. AA range:219-268

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 28kD

Human Gene ID: 83461

Human SWISS Prot NO: Q99618

Subcellular Location: Cytoplasm, cytosol.

Research Use Only