GRK 1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2476-50, ES2476-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq, Jul 2008],

Alternate Name: GRK1; RHOK; Rhodopsin kinase; RK; G protein-coupled receptor kinase 1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human GRK1. AA range:6-55

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 63kD

Human Gene ID: 6011

Human SWISS Prot NO: Q15835

Subcellular Location: Membrane; Lipid-anchor. Cell projection, cilium, photoreceptor outer segment. Subcellular location is not affected by light or dark conditions.

Research Use Only