KW-6055 is a benzylpyridine derivative and has anti-amnesic activity.

Product information

CAS Number: 63233-46-5

Molecular Weight: 299.32

Formula: C16H17N3O3

Chemical Name: N-{3-nitro-4-[(pyridin-2-yl)methyl]phenyl}butanamide

Smiles: CCCC(=O)NC1=CC(=C(CC2=CC=CC=N2)C=C1)[N+]([O-])=O

InChiKey: CZKQVCYQBJJAGG-UHFFFAOYSA-N

InChi: InChI=1S/C16H17N3O3/c1-2-5-16(20)18-14-8-7-12(15(11-14)19(21)22)10-13-6-3-4-9-17-13/h3-4,6-9,11H,2,5,10H2,1H3,(H,18,20)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

KW-6055 is a benzylpyridine derivative and has anti-amnesic activity. KW-6055 (40, 160 mg/kg, p.o.) increases the extracellular level of ACh in normal rats (257±23, 202±24%). In basal forebrain-lesioned rats, KW-6055 (40 mg/kg, p.o.) significantly increases the extracellular level of ACh (251±22%) for more than 2 hr, which is longer than in normal rats.

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