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Surber, Christian (Basel/Zurich). pH of the Skin: Issues and Challenges. Vol. 54 2018Especialidad: Dermatology Autor: Surber, Christian (Basel Zurich) Editorial: KARGER Ao: 2018 Edicin: Vol. 54 Idioma: Ingles ISBN: 9783318063844 Encuadernacin: Hard cover BOOK DETAILS: The concept of expressing acidity as the negative logarithm of the hydrogen ion concentration was defined and termed pH in the beginning of the 20th century. The general usefulness of the pH concept for life science was recognized and later gained importance to
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Especialidad: Dermatology
Autor: Surber, Christian (Basel/Zurich)
Editorial: KARGER
Año: 2018
Edición: Vol. 54
Idioma: Ingles
ISBN: 9783318063844
Encuadernación: Hard cover

BOOK DETAILS:
The concept of expressing acidity as the negative logarithm of the hydrogen ion concentration was defined and termed pH in the beginning of the 20th century. The general usefulness of the pH concept for life science was recognized and later gained importance to analytical research. Reports on results of pH measurements from living skin established the term acid mantle – the skin’s own protective shield that maintains a naturally acid pH. It is invisible to the eye but crucial to the overall wellbeing of skin. Chronic alkalization can throw this acid mantle out of balance, leading to inflammation, dermatitis, and atopic skin diseases. It is therefore no surprise, that skin pH shifts have been observed in various skin pathologies. It is also obvious that the pH in topically applied preparations may play an important role. Optimal pH and buffer capacity within topical preparations not only support stability of active ingredients and auxiliary materials, but may also increase absorption of the non-ionized species of an acidic or a basic active ingredient. They may even open up opportunities to modify and “correct” skin pH and hence accelerate barrier recovery and maintain or enhance barrier integrity. Further efforts are needed to standardize and improve pH measurements in biological media or pharmaceutical/cosmetic vehicles to increase and ensure quality, comparability, and relevance of research data. In this volume, we present a unique collection of papers that address past, present and future issues of the pH of healthy and diseased skin. It is hoped that this collection will foster future efforts in clinical and experimental skin research.
TABLE OF CONTENTS:

 
I

Preliminaries

Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp I-VIII (DOI:10.1159/000489511)

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Background and Introduction
1

The Acid Mantle: A Myth or an Essential Part of Skin Health?

Surber C. · Humbert P. · Abels C. · Maibach H.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 1-10 (DOI:10.1159/000489512)


Chemistry of pH/pH Measurement
11

Buffering Capacity

Proksch E.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 11-18 (DOI:10.1159/000489513)


19

Measurement of Skin Surface pH

du Plessis J.L. · Stefaniak A.B. · Wilhelm K.-P.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 19-25 (DOI:10.1159/000489514)


Physiology of the Skin pH
26

Skin Surface pH in Newborns: Origin and Consequences

Fluhr J.W. · Darlenski R.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 26-32 (DOI:10.1159/000489515)


33

Intrinsic and Extrinsic Factors Affecting Skin Surface pH

Farage M.A. · Hood W. · Berardesca E. · Maibach H.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 33-47 (DOI:10.1159/000489516)


48

Gender, Age, and Ethnicity as Factors That Can Influence Skin pH

Choi E.H.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 48-53 (DOI:10.1159/000489517)


54

Endogenous Factors That Can Influence Skin pH

Bíró T. · Oláh A. · Tóth B.I. · Szöllősi A.G.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 54-63 (DOI:10.1159/000489518)


64

Lipids in the Skin and pH

Wohlrab J. · Gebert A. · Neubert R.H.H.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 64-70 (DOI:10.1159/000489519)


71

Influence of pH on Skin Stem Cells and Their Differentiation

Charruyer A. · Ghadially R.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 71-78 (DOI:10.1159/000489520)


79

The Influence of Calcium on the Skin pH and Epidermal Barrier During Aging

Rinnerthaler M. · Richter K.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 79-86 (DOI:10.1159/000489521)


pH in Skin Pathophysiology
87

pH and Microbial Infections

Rippke F. · Berardesca E. · Weber T.M.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 87-94 (DOI:10.1159/000489522)


95

pH in Atopic Dermatitis

Danby S.G. · Cork M.J.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 95-107 (DOI:10.1159/000489523)


108

Role of Skin pH in Psoriasis

Bigliardi P.L.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 108-114 (DOI:10.1159/000489524)


115

pH and Acne

Schürer N.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 115-122 (DOI:10.1159/000489525)


pH in Cosmetic Products/Topical Formulations
123

pH and Buffer Capacity of Topical Formulations

Wohlrab J. · Gebert A.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 123-131 (DOI:10.1159/000489526)


132

The Relation of pH and Skin Cleansing

Blaak J. · Staib P.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 132-142 (DOI:10.1159/000489527)


143

pH and Drug Delivery

Østergaard Knudsen N. · Pommergaard Pedersen G.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 143-151 (DOI:10.1159/000489528)


152

Metamorphosis of Vehicles: Mechanisms and Opportunities

Surber C. · Knie U.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 152-165 (DOI:10.1159/000489529)


166

Influence of Topical Formulations: Lipid Lamella Organization and Lipid Composition of Stratum Corneum as a Surrogate Marker for Barrier Integrity

Dähnhardt D. · Surber C. · Dähnhardt-Pfeiffer S.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 166-172 (DOI:10.1159/000489530)


173

Skin Care Products: Age-Appropriate Cosmetics

Abels C. · Angelova-Fischer I.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 173-182 (DOI:10.1159/000489531)


183

Skin Care Products for Healthy and Diseased Skin

Surber C. · Dragicevic N. · Kottner J.
Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 183-200 (DOI:10.1159/000489532)


 
201

Author Index

Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 201 (DOI:10.1159/000489533)

Free Access


202

Subject Index

Surber C, Abels C, Maibach H (eds): pH of the Skin: Issues and Challenges. Curr Probl Dermatol. Basel, Karger, 2018, vol 54, pp 202-206 (DOI:10.1159/000489534)

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Surber, Christian (Basel/Zurich). pH of the Skin: Issues and Challenges. Vol. 54 2018

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